Anything that would use CPU cache would choke that CPU. Basically, think of anything that increases the amount of variables that need to be tracked quickly in a game. Oblivion would have tonnes of this with all of its quest interactions and AI. Anything with a good physics engine. Anything (if such still exists) that plays MIDI files (bizarre, but true).
Anything short of that and it will probably run.
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Primary
CPU: Athlon 64 X2 4400+ Mobo: Biostar N4SLI-A9 RAM: 2G Crucial (DDR400) Video: eVGA GeForce 7900 GTX (512M) Audio: HDA X-Mystique HD(s): Maxtor 300G SATA2, Samsung 400G SATA2 OS(s): WinXP x64 Pro, Vista x32 Ultimate, Gentoo x64 Monitor(s): Primary - 19" Flat Panel (1280x1024) Secondary - 19" Flat Panel (1280x1024) Tertiary - Zenith 42" Plasma TV (1024x768 res)
Many other machines... sig too short