This problem is solve by copying into Plugin directory, exact plugins or plugins that you use with ePSXe. Because if you copy into Plugin directory a lot of plugins, PCSX don't run, but if you don't copy nothing PCSX run alright. But I don't use this emulator, and don't play any games for few months, untill  Plugins, this is problem I think. If I wrong sorry, because I don't have time to check error with plugins.
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I'm sorry for my grammatic mistakes, because I'm russian 
I'm sure you guys understand me.
My Configuration:
Operating System - Windows 98 SE & XP Professional
Motherboard - Chaintech 7AJA (SocketA)
CPU - AMD Duron 750 Mhz
Memory - 384 MB SDRam
Graphics - 3dfx Voodoo3 2000 16Mb AGP
Sound - VIA AC'97
Hard Disk - Seagate Barracuda ATA IV ST340016A 40 GB
CD-ROM - 4xW/4xRW/24xR Mitsumi CR-4804TE
Monitor - 17" Viewsonic E70
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