Games that get replay time every once in a while:
Lufia 2 (Rise of the Sinistrals): My first RPG, and definitely one of the better SNES RPG's out there. Don't overlook it if you're a fan of Final Fantasy style games. The music alone is reason to play, and the graphics are among the best on the system. The story is above average Japanese swords and sorcery stuff, at least you're not chasing crystals
Nice characters and great dialogues.
Shenmue: Needs to be played badly, but an unreliable DC and lack of time kept me from it. Might introduce the lady to this game though.
The Legend of Zelda: Link's Awakening, a highly overlooked classic and definitely a great, lighthearted Zelda game. It's "A Link to the Past" - lite.
Final Fantasy 7: Used to be played every once in a while, but haven't touched it in years, unfortunately.
Dungeon Keeper 2: Epic classic, last year I replayed both the first and second game and had masses of fun.
Settlers: Well, any type of Settlers, it doesn't matter which game from the series as they all give me this lovely feeling of chilling out in a cute world, building my settlement. Often I go back to Settlers 2 though, and the remake really was a blessing as well.
Diablo 2: Sparkled by a shared addiction with my GF, I've been coming back to this game many times in the last year. Played it first in 2005, and played it again last year. Great fun, and looking forward to the third. In Summer I'll see if Titan Quest is a worthy game.